Conjunctival Matrix Metalloproteinase-9 Clinical Assessment in Early Ocular Graft versus Host Disease
نویسندگان
چکیده
منابع مشابه
Conjunctival HLA-DR and CD8 expression detected by impression cytology in ocular graft versus host disease
PURPOSE To assess the expression of human leucocyte antigen (HLA)-DR in epithelial cells and cluster of differentiation (CD8)-positive lymphocytes as possible markers of chronic ocular graft versus host disease (cGvHD) after hematological stem cell transplantation (HSCT). METHODS Twenty-seven consecutive patients with dry-eye symptoms following HSCT (24 [89%] with peripheral blood stem cell t...
متن کاملBilateral corneal ulceration in ocular graft-versus-host disease
PURPOSE To report on corneal ulceration in ocular graft-versus-host disease (GVHD). METHODS This was a retrospective, observational case series investigating corneal ulceration and perforation in a cohort of ocular GVHD patients seen between June 2007 and October 2012. RESULTS Four of 243 ocular GVHD patients developed corneal ulcerations attributable to ocular GVHD, and all four cases invo...
متن کاملFrequency of ocular manifestations of chronic graft versus host disease.
BACKGROUND With the advancement of techniques for haematopoietic cell transplantation, the number of transplant survivors is increasing rapidly and so are the chances of chronic graft versus host disease (cGVHD). The ocular manifestations of this disease have not been explored in our local population. This study was conducted to determine the frequency of ocular complications in cases of cGVHD ...
متن کاملOcular graft-versus-host disease after allogeneic transplantation.
Ocular graft-versus-host disease (GVHD) is a common complication that occurs after allogeneic transplantation. It can cause severe dry eyes that are described as having a burning, gritty, and painful sensation. Ocular GVHD can affect quality of life by causing pain and photophobia, limiting activities of daily living (e.g., reading, watching television), compromising safety while driving, and p...
متن کاملOcular manifestations of graft-versus-host disease: 10 years’ experience
PURPOSE To evaluate the ocular presentation, treatment, and clinical course of graft-versus-host disease (GVHD). DESIGN Retrospective case series. PARTICIPANTS Two hundred and forty-nine patients with systemic GVHD were included in the study. METHODS Ocular and systemic data were collected from 2003 to 2013. MAIN OUTCOME MEASURES Mortality, visual acuity, and response of ocular symptoms...
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ژورنال
عنوان ژورنال: Journal of Ophthalmology
سال: 2021
ISSN: 2090-0058,2090-004X
DOI: 10.1155/2021/9958713